The combination of dibenzazepine and a DOT1L inhibitor enables a stable maintenance of human naïve-state pluripotency in non-hypoxic conditions

Conventional human pluripotent stem cells (hPSCs), known for being in a primed state, are pivotal for both basic research and clinical applications since such cells produce various types of differentiated cells. Recent reports on PSCs shed light on the pluripotent hierarchy of stem cells and have pr...

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Detalles Bibliográficos
Autores principales: Isono, Wataru, Kawasaki, Tomoyuki, Ichida, Justin K., Ayabe, Takuya, Hiraike, Osamu, Umezawa, Akihiro, Akutsu, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770342/
https://www.ncbi.nlm.nih.gov/pubmed/33426214
http://dx.doi.org/10.1016/j.reth.2020.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770342/
https://www.ncbi.nlm.nih.gov/pubmed/33426214
http://dx.doi.org/10.1016/j.reth.2020.08.001

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