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Collagenase treatment of cartilaginous matrix promotes fusion of adjacent cartilage

In articular cartilage-repair, grafts usually fuse unsatisfactorily with surrounding host cartilage. Enzymatic dissociation of cartilaginous matrix to free chondrocytes may benefit fusion. We tested such a hypothesis with human cartilage in vitro, and with porcine cartilage in vivo. Human articular...

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Detalles Bibliográficos
Autores principales: Jiang, Ching-Chuan, Hsieh, Chang-Hsun, Liao, Chun-Jen, Chang, Wen-Hsiang, Liao, Wei-Ju, Tsai-Wu, Jyy-Jih, Chiang, Hongsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770344/
https://www.ncbi.nlm.nih.gov/pubmed/33426207
http://dx.doi.org/10.1016/j.reth.2020.05.006