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Elevated Sad1 and UNC84 Domain Containing 2 (SUN2) level inhibits cell growth and aerobic glycolysis in oral cancer through reducing the expressions of glucose transporter 1 (GLUT1) and lactate dehydrogenase A (LDHA)

BACKGROUND/PURPOSE: Oral cancer is a malignant tumor accompanied by high morbidity, mortality, and poor prognosis. Therefore, it is urgent to explore the percise regulation mechanisms underlying oral cancer. Sad1 and UNC84 Domain Containing 2 (SUN2) was considered as a tumor suppressor in some cance...

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Detalles Bibliográficos
Autores principales: Liao, Yan, Zhao, Ting, Li, Lu-Yue, Wang, Feng-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770359/
https://www.ncbi.nlm.nih.gov/pubmed/33384835
http://dx.doi.org/10.1016/j.jds.2020.08.007