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An atom-economical addition of methyl azaarenes with aromatic aldehydes via benzylic C(sp(3))–H bond functionalization under solvent- and catalyst-free conditions
A convenient practical approach for the synthesis of 2-(pyridin-2-yl)ethanols by direct benzylic addition of azaarenes and aldehydes under catalyst- and solvent-free conditions is reported. This reaction is metal-free, green, and was carried out in a facile operative environment without using any ha...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770386/ https://www.ncbi.nlm.nih.gov/pubmed/33425033 http://dx.doi.org/10.3762/bjoc.16.259 |