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Three-dimensional spheroid culture of canine hepatocyte-like cells derived from bone marrow mesenchymal stem cells

INTRODUCTION: Primary cultured hepatocytes are an important model for early safety evaluations of newly developed drugs. Many factors, however, hinder the wider applications of this technology, especially the difficulty to maintain these cells in long-term culture. To date, creating a stable supply...

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Detalles Bibliográficos
Autores principales: Nitta, Suguru, Hisasue, Masaharu, Horiguchi, Yu, Yamada, Yoko, Kikuchi, Kaoruko, Kubo, Takeaki, Igarashi, Hirotaka, Neo, Sakurako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770424/
https://www.ncbi.nlm.nih.gov/pubmed/33426221
http://dx.doi.org/10.1016/j.reth.2020.09.002