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Targeting CD38-dependent NAD(+) metabolism to mitigate multiple organ fibrosis
The processes underlying synchronous multiple organ fibrosis in systemic sclerosis (SSc) remain poorly understood. Age-related pathologies are associated with organismal decline in nicotinamide adenine dinucleotide (NAD(+)) that is due to dysregulation of NAD(+) homeostasis and involves the NADase C...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770554/ https://www.ncbi.nlm.nih.gov/pubmed/33385109 http://dx.doi.org/10.1016/j.isci.2020.101902 |