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Targeting CD38-dependent NAD(+) metabolism to mitigate multiple organ fibrosis

The processes underlying synchronous multiple organ fibrosis in systemic sclerosis (SSc) remain poorly understood. Age-related pathologies are associated with organismal decline in nicotinamide adenine dinucleotide (NAD(+)) that is due to dysregulation of NAD(+) homeostasis and involves the NADase C...

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Detalles Bibliográficos
Autores principales:	Shi, Bo, Wang, Wenxia, Korman, Benjamin, Kai, Li, Wang, Qianqian, Wei, Jun, Bale, Swarna, Marangoni, Roberta Goncalves, Bhattacharyya, Swati, Miller, Stephen, Xu, Dan, Akbarpour, Mahzad, Cheresh, Paul, Proccissi, Daniele, Gursel, Demirkan, Espindola-Netto, Jair Machado, Chini, Claudia C.S., de Oliveira, Guilherme C., Gudjonsson, Johann E., Chini, Eduardo N., Varga, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770554/ https://www.ncbi.nlm.nih.gov/pubmed/33385109 http://dx.doi.org/10.1016/j.isci.2020.101902

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