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Multi-targeted Antisense Oligonucleotide Delivery by a Framework Nucleic Acid for Inhibiting Biofilm Formation and Virulence

Biofilm formation is responsible for numerous chronic infections and represents a serious health challenge. Bacteria and the extracellular polysaccharides (EPS) cause biofilms to become adherent, toxic, resistant to antibiotics, and ultimately difficult to remove. Inhibition of EPS synthesis can pre...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxin, Xie, Xueping, Ma, Wenjuan, Zhan, Yuxi, Mao, Chenchen, Shao, Xiaoru, Lin, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770702/
https://www.ncbi.nlm.nih.gov/pubmed/34138282
http://dx.doi.org/10.1007/s40820-020-0409-3