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Tumor Microenvironment Cascade-Responsive Nanodrug with Self-Targeting Activation and ROS Regeneration for Synergistic Oxidation-Chemotherapy

Carrier-free nanodrug with exceptionally high drug payload has attracted increasing attentions. Herein, we construct a pH/ROS cascade-responsive nanodrug which could achieve tumor acidity-triggered targeting activation followed by circularly amplified ROS-triggered drug release via positive-feedback...

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Detalles Bibliográficos
Autores principales: Li, Yang, Lin, Jinyan, Wang, Peiyuan, Luo, Qiang, Zhu, Fukai, Zhang, Yun, Hou, Zhenqing, Liu, Xiaolong, Liu, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770705/
https://www.ncbi.nlm.nih.gov/pubmed/34138172
http://dx.doi.org/10.1007/s40820-020-00492-4