BRCA1/2 Mutation Status Impact on Autophagy and Immune Response: Unheralded Target

BRCA1 and possibly BRCA2 proteins may relate to the regulation of autophagy. Autophagy plays a key role in immune response from both a tumor and immune effector cell standpoint. In cells with BRCA mutations, increased autophagy leads to elevated expression of major histocompatibility complex class I...

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Detalles Bibliográficos
Autores principales: Morand, Susan, Stanbery, Laura, Walter, Adam, Rocconi, Rodney P, Nemunaitis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771003/
https://www.ncbi.nlm.nih.gov/pubmed/33409454
http://dx.doi.org/10.1093/jncics/pkaa077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771003/
https://www.ncbi.nlm.nih.gov/pubmed/33409454
http://dx.doi.org/10.1093/jncics/pkaa077

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