HDAC inhibitors Tubastatin A and SAHA affect parasite cell division and are potential anti-Toxoplasma gondii chemotherapeutics

The redirectioning of drugs in the pharmaceutical market is a well-known practice to identify new therapies for parasitic diseases. The histone deacetylase inhibitors Tubastatin A (TST) and Suberoylanilide Hydroxamic Acid (SAHA), firstly developed for cancer treatment, are effective against protozoa...

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Detalles Bibliográficos
Autores principales: Araujo-Silva, Carlla Assis, De Souza, Wanderley, Martins-Duarte, Erica S., Vommaro, Rossiane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771113/
https://www.ncbi.nlm.nih.gov/pubmed/33360687
http://dx.doi.org/10.1016/j.ijpddr.2020.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771113/
https://www.ncbi.nlm.nih.gov/pubmed/33360687
http://dx.doi.org/10.1016/j.ijpddr.2020.12.003

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