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Neutralizing antibody-dependent and -independent immune responses against SARS-CoV-2 in cynomolgus macaques

We examined the pathogenicity of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in cynomolgus macaques for 28 days to establish an animal model of COVID-19 for the development of vaccines and antiviral drugs. Cynomolgus macaques infected with SARS-CoV-2 showed body temperature rises an...

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Detalles Bibliográficos
Autores principales: Ishigaki, Hirohito, Nakayama, Misako, Kitagawa, Yoshinori, Nguyen, Cong Thanh, Hayashi, Kaori, Shiohara, Masanori, Gotoh, Bin, Itoh, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771262/
https://www.ncbi.nlm.nih.gov/pubmed/33412411
http://dx.doi.org/10.1016/j.virol.2020.12.013