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Safety and immunogenicity of a parenteral P2-VP8-P[8] subunit rotavirus vaccine in toddlers and infants in South Africa: a randomised, double-blind, placebo-controlled trial

BACKGROUND: Efficacy of live oral rotavirus vaccines is reduced in low-income compared with high-income settings. Parenteral non-replicating rotavirus vaccines might offer benefits over oral vaccines. We assessed the safety and immunogenicity of the P2-VP8-P[8] subunit rotavirus vaccine at different...

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Detalles Bibliográficos
Autores principales: Groome, Michelle J, Koen, Anthonet, Fix, Alan, Page, Nicola, Jose, Lisa, Madhi, Shabir A, McNeal, Monica, Dally, Len, Cho, Iksung, Power, Maureen, Flores, Jorge, Cryz, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771518/
https://www.ncbi.nlm.nih.gov/pubmed/28483414
http://dx.doi.org/10.1016/S1473-3099(17)30242-6