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Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes

Multiple system atrophy (MSA) is a neurodegenerative disease characterized by presence of α-synuclein-positive inclusions in the cytoplasm of oligodendrocytes. These glial cytoplasmic inclusions (GCIs) are considered an integral part of the pathogenesis of MSA, leading to demyelination and neuronal...

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Detalles Bibliográficos
Autores principales: Yoon, Ye-Seul, Ahn, Woo Jung, Ricarte, Diadem, Ortiz, Darlene, Shin, Chan Young, Lee, Seung-Jae, Lee, He-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771843/
https://www.ncbi.nlm.nih.gov/pubmed/32536617
http://dx.doi.org/10.4062/biomolther.2020.081