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Differential effects of novel kappa opioid receptor antagonists on dopamine neurons using acute brain slice electrophysiology

Activation of the kappa opioid receptor (KOR) contributes to the aversive properties of stress, and modulates key neuronal circuits underlying many neurobehavioral disorders. KOR agonists directly inhibit ventral tegmental area (VTA) dopaminergic neurons, contributing to aversive responses (Margolis...

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Detalles Bibliográficos
Autores principales: Margolis, Elyssa B., Wallace, Tanya L., Van Orden, Lori Jean, Martin, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771853/
https://www.ncbi.nlm.nih.gov/pubmed/33373369
http://dx.doi.org/10.1371/journal.pone.0232864