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Differential effects of novel kappa opioid receptor antagonists on dopamine neurons using acute brain slice electrophysiology
Activation of the kappa opioid receptor (KOR) contributes to the aversive properties of stress, and modulates key neuronal circuits underlying many neurobehavioral disorders. KOR agonists directly inhibit ventral tegmental area (VTA) dopaminergic neurons, contributing to aversive responses (Margolis...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771853/ https://www.ncbi.nlm.nih.gov/pubmed/33373369 http://dx.doi.org/10.1371/journal.pone.0232864 |