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A mechanistic framework for a priori pharmacokinetic predictions of orally inhaled drugs
The fate of orally inhaled drugs is determined by pulmonary pharmacokinetic processes such as particle deposition, pulmonary drug dissolution, and mucociliary clearance. Even though each single process has been systematically investigated, a quantitative understanding on the interaction of processes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771877/ https://www.ncbi.nlm.nih.gov/pubmed/33320846 http://dx.doi.org/10.1371/journal.pcbi.1008466 |