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A mechanistic framework for a priori pharmacokinetic predictions of orally inhaled drugs

The fate of orally inhaled drugs is determined by pulmonary pharmacokinetic processes such as particle deposition, pulmonary drug dissolution, and mucociliary clearance. Even though each single process has been systematically investigated, a quantitative understanding on the interaction of processes...

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Detalles Bibliográficos
Autores principales: Hartung, Niklas, Borghardt, Jens Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771877/
https://www.ncbi.nlm.nih.gov/pubmed/33320846
http://dx.doi.org/10.1371/journal.pcbi.1008466

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