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An IgA mimicry of IgG that binds polymeric immunoglobulin receptor for mucosa transcytosis
Most pathogens establish infection through mucosa, where secretory immunoglobulin A (sIgA) plays an ‘immune exclusion’ role in humoral defense. Extravasation of intravenously (i.v.) administrated therapeutic immunoglobulin G (IgG) mainly relies on convection and/or neonatal Fc receptor-mediated tran...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771889/ https://www.ncbi.nlm.nih.gov/pubmed/33381681 http://dx.doi.org/10.1093/abt/tbaa014 |