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An IgA mimicry of IgG that binds polymeric immunoglobulin receptor for mucosa transcytosis

Most pathogens establish infection through mucosa, where secretory immunoglobulin A (sIgA) plays an ‘immune exclusion’ role in humoral defense. Extravasation of intravenously (i.v.) administrated therapeutic immunoglobulin G (IgG) mainly relies on convection and/or neonatal Fc receptor-mediated tran...

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Detalles Bibliográficos
Autores principales: Mao, Changchuin, Near, Richard, Shibad, Varuna, Zhong, Xuemei, Gao, Wenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771889/
https://www.ncbi.nlm.nih.gov/pubmed/33381681
http://dx.doi.org/10.1093/abt/tbaa014