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Frequency and Association Of GSTM1 and GSTT1 Gene Polymorphisms with Survival in Breast Cancer Patients

OBJECTIVE: Glutathione S-transferase M1 and T1 (GSTM1 and GSTT1) are the key detoxification enzymes of xenobiotics, including chemotherapeutic drugs. The deletion polymorphisms of GSTM1 and GSTT1 genes are associated with reduced enzyme activity that influenced clinical outcomes of chemotherapeutic...

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Detalles Bibliográficos
Autores principales: Tangkheunkan, Phakarat, Harncharoen, Kitiphong, Thanasitthichai, Somchai, Tiwawech, Danai, Purisa, Wichai, Saelee, Pensri, Wattanalai, Ruxjinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771926/
https://www.ncbi.nlm.nih.gov/pubmed/32856852
http://dx.doi.org/10.31557/APJCP.2020.21.8.2251