Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis

Bone remodeling involves a balance between bone resorption and formation. The mechanisms underlying bone remodeling are not well understood. DEF6 is recently identified as a novel loci associated with bone mineral density. However, it is unclear how Def6 impacts bone remodeling. We identify Def6 as...

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Detalles Bibliográficos
Autores principales: Deng, Zhonghao, Ng, Courtney, Inoue, Kazuki, Chen, Ziyu, Xia, Yuhan, Hu, Xiaoyu, Greenblatt, Matthew, Pernis, Alessandra, Zhao, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771961/
https://www.ncbi.nlm.nih.gov/pubmed/33373293
http://dx.doi.org/10.7554/eLife.59659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771961/
https://www.ncbi.nlm.nih.gov/pubmed/33373293
http://dx.doi.org/10.7554/eLife.59659

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