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Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
Bone remodeling involves a balance between bone resorption and formation. The mechanisms underlying bone remodeling are not well understood. DEF6 is recently identified as a novel loci associated with bone mineral density. However, it is unclear how Def6 impacts bone remodeling. We identify Def6 as...
Autores principales: | Deng, Zhonghao, Ng, Courtney, Inoue, Kazuki, Chen, Ziyu, Xia, Yuhan, Hu, Xiaoyu, Greenblatt, Matthew, Pernis, Alessandra, Zhao, Baohong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771961/ https://www.ncbi.nlm.nih.gov/pubmed/33373293 http://dx.doi.org/10.7554/eLife.59659 |
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