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Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2

UDP-glucose:glycoprotein glucosyltransferase (UGGT) 1 and 2 are central hubs in the chaperone network of the endoplasmic reticulum (ER), acting as gatekeepers to the early secretory pathway, yet little is known about their cellular clients. These two quality control sensors control lectin chaperone...

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Detalles Bibliográficos
Autores principales: Adams, Benjamin M, Canniff, Nathan P, Guay, Kevin P, Larsen, Ida Signe Bohse, Hebert, Daniel N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771966/
https://www.ncbi.nlm.nih.gov/pubmed/33320095
http://dx.doi.org/10.7554/eLife.63997