Cargando…

MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression

The severity of sepsis may be associated with excessive inflammation, thus leading to acute liver injury. MicroRNA-21 is highly expressed in the liver of a variety of inflammation-related diseases, and PPARα is also proved to participate in regulating inflammation. In the present study, the LPS-indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Xianjin, Wu, Miao, Tian, Dan, Zhou, Jianlin, Wang, Lu, Zhan, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772039/
https://www.ncbi.nlm.nih.gov/pubmed/33424957
http://dx.doi.org/10.1155/2020/6633022