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MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression
The severity of sepsis may be associated with excessive inflammation, thus leading to acute liver injury. MicroRNA-21 is highly expressed in the liver of a variety of inflammation-related diseases, and PPARα is also proved to participate in regulating inflammation. In the present study, the LPS-indu...
Autores principales: | Du, Xianjin, Wu, Miao, Tian, Dan, Zhou, Jianlin, Wang, Lu, Zhan, Liying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772039/ https://www.ncbi.nlm.nih.gov/pubmed/33424957 http://dx.doi.org/10.1155/2020/6633022 |
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