Cleavage of HMGB1 by Proteolytic Enzymes Associated with Inflammatory Conditions

Extracellular HMGB1 acts as an alarmin in multiple autoimmune diseases. While its release and functions have been extensively studied, there is a substantial lack of knowledge regarding HMGB1 regulation at the site of inflammation. Herein we show that enzymes present in arthritis-affected joints pro...

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Detalles Bibliográficos
Autores principales: Sowinska, Agnieszka, Rensing, Merlin, Klevenvall, Lena, Neog, Manoj, Lundbäck, Peter, Harris, Helena Erlandsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772184/
https://www.ncbi.nlm.nih.gov/pubmed/33391251
http://dx.doi.org/10.3389/fimmu.2020.448262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772184/
https://www.ncbi.nlm.nih.gov/pubmed/33391251
http://dx.doi.org/10.3389/fimmu.2020.448262

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