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Cleavage of HMGB1 by Proteolytic Enzymes Associated with Inflammatory Conditions
Extracellular HMGB1 acts as an alarmin in multiple autoimmune diseases. While its release and functions have been extensively studied, there is a substantial lack of knowledge regarding HMGB1 regulation at the site of inflammation. Herein we show that enzymes present in arthritis-affected joints pro...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772184/ https://www.ncbi.nlm.nih.gov/pubmed/33391251 http://dx.doi.org/10.3389/fimmu.2020.448262 |