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Melatonin Inhibits Glucose-Induced Apoptosis in Osteoblastic Cell Line Through PERK-eIF2α-ATF4 Pathway

Osteoporosis is a common disease resulting in deteriorated microarchitecture and decreased bone mass. In type 2 diabetes patients, the incidence of osteoporosis is significantly higher accompanied by increased apoptosis of osteoblasts. In this study, using the osteoblastic cell line MC3T3-E1, we sho...

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Detalles Bibliográficos
Autores principales: Zhou, Renyi, Ma, Yue, Tao, Zhengbo, Qiu, Shui, Gong, Zunlei, Tao, Lin, Zhu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772242/
https://www.ncbi.nlm.nih.gov/pubmed/33390989
http://dx.doi.org/10.3389/fphar.2020.602307