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Protocol to assess the efficacy of carnosine supplementation in mitigating the adverse cardiovascular responses to particulate matter (PM) exposure: the Nucleophilic Defense Against PM Toxicity (NEAT) trial

INTRODUCTION: Exposure to airborne particulate matter (PM) is associated with cardiovascular disease. These outcomes are believed to originate from pulmonary oxidative stress and the systemic delivery of oxidised biomolecules (eg, aldehydes) generated in the lungs. Carnosine is an endogenous di-pept...

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Detalles Bibliográficos
Autores principales: O'Toole, Timothy E., Amraotkar, Alok A., DeFilippis, Andrew P., Rai, Shesh N., Keith, Rachel J., Baba, Shahid P., Lorkiewicz, Pawel, Crandell, Catherine E., Pariser, Gina L., Wingard, Christopher J., Pope III, C. Arden, Bhatnagar, Aruni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772308/
https://www.ncbi.nlm.nih.gov/pubmed/33372072
http://dx.doi.org/10.1136/bmjopen-2020-039118