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Protocol to assess the efficacy of carnosine supplementation in mitigating the adverse cardiovascular responses to particulate matter (PM) exposure: the Nucleophilic Defense Against PM Toxicity (NEAT) trial
INTRODUCTION: Exposure to airborne particulate matter (PM) is associated with cardiovascular disease. These outcomes are believed to originate from pulmonary oxidative stress and the systemic delivery of oxidised biomolecules (eg, aldehydes) generated in the lungs. Carnosine is an endogenous di-pept...
Autores principales: | O'Toole, Timothy E., Amraotkar, Alok A., DeFilippis, Andrew P., Rai, Shesh N., Keith, Rachel J., Baba, Shahid P., Lorkiewicz, Pawel, Crandell, Catherine E., Pariser, Gina L., Wingard, Christopher J., Pope III, C. Arden, Bhatnagar, Aruni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772308/ https://www.ncbi.nlm.nih.gov/pubmed/33372072 http://dx.doi.org/10.1136/bmjopen-2020-039118 |
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