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Alternative splicing: Human disease and quantitative analysis from high-throughput sequencing

Alternative splicing contributes to the majority of protein diversity in higher eukaryotes by allowing one gene to generate multiple distinct protein isoforms. It adds another regulation layer of gene expression. Up to 95% of human multi-exon genes undergo alternative splicing to encode proteins wit...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772363/
https://www.ncbi.nlm.nih.gov/pubmed/33425250
http://dx.doi.org/10.1016/j.csbj.2020.12.009