Carnosine Stimulates Macrophage-Mediated Clearance of Senescent Skin Cells Through Activation of the AKT2 Signaling Pathway by CD36 and RAGE

Background: Macrophages can selectively recognize and eliminate senescent cells, but this function is impaired with age, resulting in excessive accumulation of senescent cells in the skin, which ultimately causes skin aging. Therefore, enhancing the immune surveillance ability of macrophages to clea...

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Detalles Bibliográficos
Autores principales: Li, Xuenan, Yang, Kaiye, Gao, Shuang, Zhao, Jungang, Liu, Guangrong, Chen, Yu, Lin, Haojie, Zhao, Wengang, Hu, Zhenlin, Xu, Nuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772392/
https://www.ncbi.nlm.nih.gov/pubmed/33390976
http://dx.doi.org/10.3389/fphar.2020.593832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772392/
https://www.ncbi.nlm.nih.gov/pubmed/33390976
http://dx.doi.org/10.3389/fphar.2020.593832

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