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Carnosine Stimulates Macrophage-Mediated Clearance of Senescent Skin Cells Through Activation of the AKT2 Signaling Pathway by CD36 and RAGE
Background: Macrophages can selectively recognize and eliminate senescent cells, but this function is impaired with age, resulting in excessive accumulation of senescent cells in the skin, which ultimately causes skin aging. Therefore, enhancing the immune surveillance ability of macrophages to clea...
Autores principales: | Li, Xuenan, Yang, Kaiye, Gao, Shuang, Zhao, Jungang, Liu, Guangrong, Chen, Yu, Lin, Haojie, Zhao, Wengang, Hu, Zhenlin, Xu, Nuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772392/ https://www.ncbi.nlm.nih.gov/pubmed/33390976 http://dx.doi.org/10.3389/fphar.2020.593832 |
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