In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N-Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis

Leishmaniasis are group of neglected diseases with worldwide distribution that affect about 12 million people. The current treatment is limited and may cause severe adverse effects, and thus, the search for new drugs more effective and less toxic is relevant. We have previously investigated the immu...

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Detalles Bibliográficos
Autores principales: Silva, Dahara Keyse Carvalho, Teixeira, Jessicada Silva, Moreira, Diogo Rodrigo Magalhães, da Silva, Tiago Fernandes, Barreiro, Eliezer Jesus de Lacerda, de Freitas, Humberto Fonseca, Pita, Samuel Silva da Rocha, Teles, André Lacerda Braga, Guimarães, Elisalva Teixeira, Soares, Milena Botelho Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772393/
https://www.ncbi.nlm.nih.gov/pubmed/33390966
http://dx.doi.org/10.3389/fphar.2020.590544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772393/
https://www.ncbi.nlm.nih.gov/pubmed/33390966
http://dx.doi.org/10.3389/fphar.2020.590544

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