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Cytokines in CAR T Cell–Associated Neurotoxicity

Chimeric antigen receptor (CAR) T cells provide new therapeutic options for patients with relapsed/refractory hematologic malignancies. However, neurotoxicity is a frequent, and potentially fatal, complication. The spectrum of manifestations ranges from delirium and language dysfunction to seizures,...

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Detalles Bibliográficos
Autores principales: Gust, Juliane, Ponce, Rafael, Liles, W. Conrad, Garden, Gwenn A., Turtle, Cameron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772425/
https://www.ncbi.nlm.nih.gov/pubmed/33391257
http://dx.doi.org/10.3389/fimmu.2020.577027