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Insights Into Development and Progression of Idiopathic Pulmonary Fibrosis From Single Cell RNA Studies

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited therapeutic options. The current model suggests that chronic or repetitive “micro-injuries” of the alveolar epithelium lead to activation and proliferation of fibroblasts and excessive extracellular matrix (ECM)...

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Detalles Bibliográficos
Autores principales: Nemeth, Julia, Schundner, Annika, Frick, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772461/
https://www.ncbi.nlm.nih.gov/pubmed/33392232
http://dx.doi.org/10.3389/fmed.2020.611728