A Mineralocorticoid Receptor Deficiency in Myeloid Cells Reduces Liver Steatosis by Impairing Activation of CD8(+) T Cells in a Nonalcoholic Steatohepatitis Mouse Model

BACKGROUND AND AIMS: The mineralocorticoid receptor (MR) and renin-angiotensin-aldosterone system (RAAS) are implicated in non-alcoholic liver fatty disease (NALFD). However, inflammatory mechanisms linking MR and RAAS with disease pathology remain unclear. Here we aimed to evaluate the contribution...

Descripción completa

Detalles Bibliográficos
Autores principales: Muñoz-Durango, Natalia, Arrese, Marco, Hernández, Alejandra, Jara, Evelyn, Kalergis, Alexis M., Cabrera, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772468/
https://www.ncbi.nlm.nih.gov/pubmed/33391254
http://dx.doi.org/10.3389/fimmu.2020.563434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772468/
https://www.ncbi.nlm.nih.gov/pubmed/33391254
http://dx.doi.org/10.3389/fimmu.2020.563434

Ejemplares similares