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Moieties of Complement iC3b Recognized by the I-domain of Integrin αXβ2

Complement fragment iC3b serves as a major opsonin for facilitating phagocytosis via its interaction with complement receptors CR3 and CR4, also known by their leukocyte integrin family names, αMβ2 and αXβ2, respectively. Although there is general agreement that iC3b binds to the αM and αX I-domains...

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Detalles Bibliográficos
Autores principales: Choi, Jeongsuk, Buyannemekh, Dolgorsuren, Nham, Sang-Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772510/
https://www.ncbi.nlm.nih.gov/pubmed/33372665
http://dx.doi.org/10.14348/molcells.2020.0197