Donor-Specific Transcriptomic Analysis of Alzheimer's Disease-Associated Hypometabolism Highlights a Unique Donor, Ribosomal Proteins and Microglia

Alzheimer’s disease (AD) starts decades before clinical symptoms appear. Low-glucose utilization in regions of the cerebral cortex marks early AD. To identify these regions, we conducted a voxel-wise meta-analysis of previous studies conducted with positron emission tomography that compared AD patie...

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Detalles Bibliográficos
Autores principales: Patel, Sejal, Howard, Derek, Man, Alana, Schwartz, Deborah, Jee, Joelle, Felsky, Daniel, Pausova, Zdenka, Paus, Tomas, French, Leon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772516/
https://www.ncbi.nlm.nih.gov/pubmed/33234543
http://dx.doi.org/10.1523/ENEURO.0255-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772516/
https://www.ncbi.nlm.nih.gov/pubmed/33234543
http://dx.doi.org/10.1523/ENEURO.0255-20.2020

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