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Cyclin-dependent kinase inhibitors p21 and p27 function as critical regulators of liver regeneration following 90% hepatectomy in the rat

BACKGROUND: Liver reduction is the main curative treatment for primary liver cancer, but its use remains limited as liver regeneration requires a minimum of 30% functional parenchyma. AIM: To study the dynamics of the liver regeneration process and consequent behavior of cell cycle regulators in rat...

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Detalles Bibliográficos
Autores principales: Moniaux, Nicolas, Lacaze, Laurence, Gothland, Adélie, Deshayes, Alice, Samuel, Didier, Faivre, Jamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772727/
https://www.ncbi.nlm.nih.gov/pubmed/33442448
http://dx.doi.org/10.4254/wjh.v12.i12.1198