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Cyclin-dependent kinase inhibitors p21 and p27 function as critical regulators of liver regeneration following 90% hepatectomy in the rat
BACKGROUND: Liver reduction is the main curative treatment for primary liver cancer, but its use remains limited as liver regeneration requires a minimum of 30% functional parenchyma. AIM: To study the dynamics of the liver regeneration process and consequent behavior of cell cycle regulators in rat...
Autores principales: | Moniaux, Nicolas, Lacaze, Laurence, Gothland, Adélie, Deshayes, Alice, Samuel, Didier, Faivre, Jamila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772727/ https://www.ncbi.nlm.nih.gov/pubmed/33442448 http://dx.doi.org/10.4254/wjh.v12.i12.1198 |
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