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HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails
G protein-coupled receptors (GPCRs) are the most common pharmacological target in human clinical practice. To perform their functions, many GPCRs must accumulate inside primary cilia, microtubule-based plasma membrane protrusions working as cellular antennae. Nevertheless, the molecular mechanisms u...
Autores principales: | Barbeito, Pablo, Tachibana, Yuki, Martin-Morales, Raquel, Moreno, Paula, Mykytyn, Kirk, Kobayashi, Tetsuo, Garcia-Gonzalo, Francesc R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772773/ https://www.ncbi.nlm.nih.gov/pubmed/33372037 http://dx.doi.org/10.26508/lsa.202000746 |
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