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Paneth cell–derived growth factors support tumorigenesis in the small intestine

Paneth cells (PCs) are small intestinal epithelial cells that secrete antimicrobial peptides and growth factors, such as Wnt ligands. Intriguingly, the context in which PC-derived Wnt secretion is relevant in vivo remains unknown as intestinal epithelial ablation of Wnt does not affect homeostatic p...

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Detalles Bibliográficos
Autores principales: Chen, Qing, Suzuki, Kohei, Sifuentes-Dominguez, Luis, Miyata, Naoteru, Song, Jie, Lopez, Adam, Starokadomskyy, Petro, Gopal, Purva, Dozmorov, Igor, Tan, Shuai, Ge, Bujun, Burstein, Ezra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772774/
https://www.ncbi.nlm.nih.gov/pubmed/33372038
http://dx.doi.org/10.26508/lsa.202000934