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Paneth cell–derived growth factors support tumorigenesis in the small intestine
Paneth cells (PCs) are small intestinal epithelial cells that secrete antimicrobial peptides and growth factors, such as Wnt ligands. Intriguingly, the context in which PC-derived Wnt secretion is relevant in vivo remains unknown as intestinal epithelial ablation of Wnt does not affect homeostatic p...
Autores principales: | Chen, Qing, Suzuki, Kohei, Sifuentes-Dominguez, Luis, Miyata, Naoteru, Song, Jie, Lopez, Adam, Starokadomskyy, Petro, Gopal, Purva, Dozmorov, Igor, Tan, Shuai, Ge, Bujun, Burstein, Ezra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772774/ https://www.ncbi.nlm.nih.gov/pubmed/33372038 http://dx.doi.org/10.26508/lsa.202000934 |
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