Modulation of Aub–TDRD interactions elucidates piRNA amplification and germplasm formation

Aub guided by piRNAs ensures genome integrity by cleaving retrotransposons, and genome propagation by trapping mRNAs to form the germplasm that instructs germ cell formation. Arginines at the N-terminus of Aub (Aub–NTRs) interact with Tudor and other Tudor domain–containing proteins (TDRDs). Aub–TDR...

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Detalles Bibliográficos
Autores principales: Vrettos, Nicholas, Maragkakis, Manolis, Alexiou, Panagiotis, Sgourdou, Paraskevi, Ibrahim, Fadia, Palmieri, Daniel, Kirino, Yohei, Mourelatos, Zissimos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772777/
https://www.ncbi.nlm.nih.gov/pubmed/33376130
http://dx.doi.org/10.26508/lsa.202000912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772777/
https://www.ncbi.nlm.nih.gov/pubmed/33376130
http://dx.doi.org/10.26508/lsa.202000912

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