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Modulation of Aub–TDRD interactions elucidates piRNA amplification and germplasm formation
Aub guided by piRNAs ensures genome integrity by cleaving retrotransposons, and genome propagation by trapping mRNAs to form the germplasm that instructs germ cell formation. Arginines at the N-terminus of Aub (Aub–NTRs) interact with Tudor and other Tudor domain–containing proteins (TDRDs). Aub–TDR...
Autores principales: | Vrettos, Nicholas, Maragkakis, Manolis, Alexiou, Panagiotis, Sgourdou, Paraskevi, Ibrahim, Fadia, Palmieri, Daniel, Kirino, Yohei, Mourelatos, Zissimos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772777/ https://www.ncbi.nlm.nih.gov/pubmed/33376130 http://dx.doi.org/10.26508/lsa.202000912 |
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