Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models

p53 is the most frequently mutated gene in human cancers. Li-Fraumeni syndrome patients inheriting heterozygous p53 mutations often have a much-increased risk to develop cancer(s) at early ages. Recent studies suggest that some individuals inherited p53 mutations do not have the early onset or high...

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Detalles Bibliográficos
Autores principales: Chan, Chang S, Sun, Yvonne, Ke, Hua, Zhao, Yuhan, Belete, Merzu, Zhang, Cen, Feng, Zhaohui, Levine, Arnold J, Hu, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772779/
https://www.ncbi.nlm.nih.gov/pubmed/33376133
http://dx.doi.org/10.26508/lsa.202000952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772779/
https://www.ncbi.nlm.nih.gov/pubmed/33376133
http://dx.doi.org/10.26508/lsa.202000952

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