The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells

The RNA polymerase II (RNAPII) associated factor 1 complex (Paf1C) plays critical roles in modulating the release of paused RNAPII into productive elongation. However, regulation of Paf1C-mediated promoter-proximal pausing is complex and context dependent. In fact, in cancer cell lines, opposing mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Li, Paszkowski-Rogacz, Maciej, Mircetic, Jovan, Chakraborty, Debojyoti, Buchholz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772781/
https://www.ncbi.nlm.nih.gov/pubmed/33376128
http://dx.doi.org/10.26508/lsa.202000792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772781/
https://www.ncbi.nlm.nih.gov/pubmed/33376128
http://dx.doi.org/10.26508/lsa.202000792

Ejemplares similares