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Convex hulls in hamming space enable efficient search for similarity and clustering of genomic sequences

BACKGROUND: In molecular epidemiology, comparison of intra-host viral variants among infected persons is frequently used for tracing transmissions in human population and detecting viral infection outbreaks. Application of Ultra-Deep Sequencing (UDS) immensely increases the sensitivity of transmissi...

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Detalles Bibliográficos
Autores principales: Campo, David S., Khudyakov, Yury
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772912/
https://www.ncbi.nlm.nih.gov/pubmed/33375937
http://dx.doi.org/10.1186/s12859-020-03811-z