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Evolution of drug resistance in HIV protease

BACKGROUND: Drug resistance is a critical problem limiting effective antiviral therapy for HIV/AIDS. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to identify protease mutants for...

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Detalles Bibliográficos
Autores principales: Shah, Dhara, Freas, Christopher, Weber, Irene T., Harrison, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772915/
https://www.ncbi.nlm.nih.gov/pubmed/33375936
http://dx.doi.org/10.1186/s12859-020-03825-7