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Inferring the three-dimensional structures of the X-chromosome during X-inactivation

The Hi-C experiment can capture the genome-wide spatial proximities of the DNA, based on which it is possible to computationally reconstruct the three-dimensional (3D) structures of chromosomes. The transcripts of the long non-coding RNA (lncRNA) Xist spread throughout the entire X-chromosome and al...

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Detalles Bibliográficos
Autores principales: Zhu, Hao, Wang, Nan, Sun, Jonathan Z., Pandey, Ras B., Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772933/
https://www.ncbi.nlm.nih.gov/pubmed/31698618
http://dx.doi.org/10.3934/mbe.2019369